Systematic Reviews encompasses all aspects of the design, conduct and reporting of systematic reviews. The journal aims to publish high quality systematic review products including systematic review protocols, systematic reviews related to a very broad definition of health, rapid reviews, updates of already completed systematic reviews, and methods research related to the science of systematic reviews, such as decision modeling. The journal also aims to ensure that the results of all well-conducted systematic reviews are published, regardless of their outcome.


  • David Moher, Ottawa Hospital Research Institute
  • Paul G Shekelle, RAND Corporation
  • Lesley A Stewart, CRD, University of York


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  • Supporting systematic reviews using LDA-based document representations

    Text mining methods to identify relevant studies during the screening stage of a systematic review are becoming more popular. During automatic citation screening, the LDA topic modelling approach results in a more informative representation of studies than the BOW model.

    Systematic Reviews 2015, 4:172
  • Do alternative methods for analysing count data produce similar estimates?

    Analyzing count outcomes in randomized trials using different methods during meta-analyses yielded estimates of an intervention effect that were similar in both averages and variances. Implications when pooling count analyses using dichotomisation or time to the first events are highlighted.

    Systematic Reviews 2015, 4:163
  • Behavioral interventions evaluated through the RE-AIM framework

    The RE-AIM framework was developed to improve the reporting of internal and external validity of interventions to determine public health impact. However, there are inconsistencies in reporting each dimension and inaccuracies in reporting indicators within the dimensions.

    Systematic Reviews 2015, 4:155
  • Impact of resuscitation fluids on the microcirculation after haemorrhagic shock

    Whether modern resuscitation strategies after haemorrhagic shock should take into account microcirculatory dysfunction as well as global haemodynamic parameters is currently debated; this systematic review will collate pre-clinical data on the impact of resuscitation fluids on the microcirculatory function following haemorrhagic shock.

    Systematic Reviews 2015, 4:135
  • Cochrane systematic reviews and co-publication

    Adherence to the co-publication standards for Cochrane reviews published in the Cochrane Database of Systematic Reviews and traditional medical journals were moderate; overall findings support co-publication as a way to increase dissemination effectiveness.

    Systematic Reviews 2015, 4:118



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Systematic reviews reporting

Systematic Reviews advocates the complete and transparent reporting of research. Authors are required to adhere to the PRISMA Statement for any submitted systematic reviews, and required to follow the PRISMA-P Statement for protocol articles. The Editors also encourage authors to follow any relevant extensions to the PRISMA Statement, available from the EQUATOR Network.

Call for papers: Qualitative Methods thematic series

Systematic Reviews is inviting submissions to its new cross-journal thematic series, 'Qualitative Methods, Trials and Systematic Reviews'. For more information, please see here.

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Editors' profiles

David Moher

David MoherDr. David Moher is a senior scientist at the Clinical Epidemiology Program, Ottawa Hospital Research Institute, and Associate Professor, Department of Epidemiology and Community Medicine, University of Ottawa. Dr. Moher has been involved in systematic reviews for more than 20 years and has made contributions to the conduct and reporting of systematic reviews. Dr. Moher is associated with many journals, is a member of the advisory board for the International Congress on Peer Review and Biomedical Publication, and a member of the EQUATOR Network's steering group.

Paul Shekelle

Paul ShekelleIn addition to currently serving as a Staff Physician at the West Los Angeles Veterans Affairs Medical Center, Dr. Shekelle has served as the Director of the Southern California Evidence-based Practice Center for the RAND Corporation since 1997. He is also a Professor of Medicine at the University of California, Los Angeles (UCLA) School of Medicine. He is widely recognized in the field of guidelines, quality measurement, and evidence-based medicine. Dr. Shekelle has extensive experience in the health care arena and was previously the methodologist for the Agency for Health Care Policy and Research (now the Agency for Healthcare Research and Quality [AHRQ]) Low-Back Guidelines Panel, and he has participated in a number of other guideline development activities. He is currently the chair of the Clinical Guidelines Committee of the American College of Physicians.

Lesley Stewart

Lesley Stewart Professor Lesley Stewart is Director of the Centre for Reviews and Dissemination (CRD) at the University of York and is a National Institute for Health Research (NIHR) Senior Investigator. Lesley has been involved in evidence synthesis in healthcare since the late 1980's, previously running the Medical Research Council Clinical Trials Unit meta-analysis research programme. Together with colleagues in Cambridge and Oxford, she helped establish the methodology and framework for individual patient data (IPD) reviews and was a founding member of the Cochrane Collaboration. Her research interests include the avoidance of bias and development of IPD methods and approaches to systematic review. Recently, she has instigated the development of PROSPERO an international register for the prospective registration of systematic reviews.
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ISSN: 2046-4053